High blood viscosity linked to increased risk of death in hospitalized Covid patients: Study
20 July, 2022 | Vaishali Sharma
Hospitalized COVID-19 patients with a high estimated blood viscosity are more likely to die from complications. Blood viscosity raises the risk of blood clots and restricts blood flow to small arte...
Hospitalized COVID-19 patients with a high estimated blood viscosity are more likely to die from complications. Blood viscosity raises the risk of blood clots and restricts blood flow to small arteries. This blood thickness measurement can be used to predict mortality.
This study was published in the Journal of the American College of Cardiology. This is the first large-scale study of COVID-19 patients in which blood viscosity was examined as a predictor of mortality. A simple assessment of blood viscosity proved more reliable than traditional tests of inflammation and the blood clotting biomarker D-dimer in identifying hospitalised patients at risk of dying from COVID-19 issues.
Blood viscosity is not directly assessed in hospitalised patients, but doctors generally measure hematocrit and globulins (the difference between total protein and albumin) in all patients for diagnosis and monitoring therapy. Blood viscosity may be calculated using the hematocrit and globulins. The estimate of blood viscosity was shown to be more significantly linked with mortality in COVID-19 participants than other frequently used risk stratification variables in this study. This is a simple computation that might be added to electronic medical records or lab sheets to increase the probability of survival in COVID-19 hospitalised patients.
Acute phase reactants (fibrinogen, macroglobulins) associated with acute COVID-19 infections increase blood viscosity. Blood viscosity is a measure of both acute phase reactants and cellular components that can increase during infection. To decrease the severity of the acute phase reaction to COVID-19, clinicians may consider therapeutic heparin, hydration, or glucocorticoid escalation when blood viscosity is high.
“This study highlights the significance of assessing blood viscosity in COVID-19 patients early in their hospitalisation, which is easily obtainable through standard lab testing.” The findings, according to Dr. Rosenson, “may assist select the appropriate treatment plan for at-risk patients and help improve outcomes.” We are now researching the impact of therapeutic heparin on the likelihood of problems during acute COVID-19 infections, which may assist patients with high blood viscosity.”